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CALCIUM/STRONTIUM HYDROXYAPATITE.

Valuable / ORAL CARE

A sophisticated biomimetic mineral complex that bridges the gap between dental remineralization and advanced dermal repair. This multi-functional ingredient serves as a structural scaffold to support the skin's matrix while acting as a potent sensory buffer for high-performance actives.

Sensory Inhibitor Skin Conditioning Agent Barrier Repair Bulking Agent Abrasive

Science

This mineral functions as a sensory inhibitor where the strontium ions modulate nerve responses to reduce the stinging and irritation typically associated with AHAs or retinoids. Simultaneously, its hydroxyapatite structure provides a bio-available source of minerals that promote the synthesis of collagen, elastin, and proteoglycans, accelerating the repair of the skin barrier.


Research

High confidence
Effective range 1–6.5%
Optimal

3.5%

Key findings

  1. 01 Strontium-doped nanohydroxyapatite (25%) demonstrated superior mineral deposition and remineralization compared to standard agents in oral environments.
  2. 02 Safety assessments confirm rapid dissolution in biological fluids at 3.1%, ensuring metabolic safety.
  3. 03 Historical data from the IECIC (2021) establishes a safety ceiling of 6.5% for leave-on topical applications.

Transparency

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Due to its dual role as a bulking agent and an expensive mineral, it is frequently included at negligible levels (<0.1%) for label claims. To achieve measurable sensory inhibition or barrier support, concentrations should ideally exceed 1%.


The Formula

Solubility
Water
Optimal pH 5 – 8.5
0 7 14

Stability

As an insoluble mineral, it must be suspended carefully; it is highly unstable in acidic environments (pH < 4.5), where the crystalline structure dissolves into ionic components.

Synergies

  • Retinoids
  • Alpha Hydroxy Acids
  • Peptides
  • Hyaluronic Acid

Conflicts

  • Low pH Ascorbic Acid
  • Salicylic Acid
  • High concentrations of Disodium EDTA
  • Glycolic Acid formulations below pH 4.5

Safety

CIR Status
Not reviewed
Max tested
6.5%
Pregnancy
Safe
Sensitization risk Low

SCCS recognizes hydroxyapatite safety up to 29.5% in oral care; however, needle-shaped nano-particles are strictly excluded from use due to potential cellular toxicity.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional mineral additive for sensitive skin formulations, providing unique sensory-calming benefits and structural support when used at therapeutic levels.


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