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CALCIUM FLUORIDE.

Valuable CAS 7789-75-5 / ANTIPLAQUE, ORAL CARE

A mineral-based salt primarily utilized for its remineralizing properties in oral hygiene and its emerging role in supporting structural skin integrity. Known for its high stability, it serves as a slow-release reservoir of ions that help reinforce hard tissues and maintain connective tissue resilience.

Oral care agent Anti-plaque Abrasive Opacifying Skin conditioning

Science

In topical applications, it functions as a bio-mineral that supports the scaffolding of the skin, potentially assisting in the maintenance of collagen elasticity and connective tissue tone. In oral environments, it acts as a pH-sensitive reservoir, releasing fluoride ions when the environment becomes acidic (pH < 6.0) to facilitate the formation of acid-resistant fluorapatite.


Research

High confidence
Effective range 0.05–0.15%
Optimal

0.15%

Key findings

  1. 01 Standardized dental assessments confirm 0.15% fluoride equivalent as the gold standard for caries prevention and enamel reinforcement.
  2. 02 Research into high-concentration systems (5000 ppm) demonstrates superior surface remineralization for white spot lesions.
  3. 03 Historical tissue salt data suggests 6X/12X dilutions support skin elasticity, though large-scale dermatological validation remains sparse.

Transparency

Commonly dusted
Min. effective
0.01%
Red flag below
0.05%

Because it is often included as a 'Schüssler tissue salt' for elasticity, it is frequently found in homeopathic concentrations (6X/12X) that are far below a level required for physiological mineral impact on the skin barrier.


The Formula

Solubility
Water
Optimal pH 4.2 – 8
0 7 14

Stability

Highly insoluble in water (0.015 g/L). Formulation pH must be kept above 4.2; dropping below this threshold can trigger a reaction that forms hydrofluoric acid, compromising both safety and stability.

Synergies

  • Calcium Carbonate
  • Hydroxyapatite
  • Glycerin

Conflicts

  • Strong mineral acids
  • High concentrations of phosphate ions

Safety

CIR Status
Safe as used
Max tested
0.15%
Pregnancy
Safe
Sensitization risk Low

The 0.15% maximum concentration is calculated based on total Fluoride content. In various jurisdictions, use is restricted to oral care with mandatory age-specific labeling.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An essential mineral for structural oral health that offers niche benefits for skin elasticity, provided formulation pH is strictly controlled.


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