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CALCIUM DODECYLBENZENESULFONATE.

Questionable CAS 26264-06-2 / CLEANSING, SURFACTANT - CLEANSING

A robust anionic surfactant and emulsifying agent primarily utilized to stabilize oil-in-water formulations and enhance cleansing efficiency. While highly effective at lifting debris and maintaining emulsion integrity, its potency requires careful concentration management to ensure skin compatibility.

Surfactant Cleansing Agent Emulsifier

Science

This amphiphilic molecule features a lipophilic dodecylbenzene tail and a hydrophilic sulfonate head. It functions by lowering the interfacial tension between water and oil, facilitating the creation of stable micelles that encapsulate and remove excess sebum, environmental pollutants, and lipid-based impurities from the skin surface.


Research

Medium confidence
Effective range 1–4%
Optimal

3%

Key findings

  1. 01 Amended safety assessments indicate that concentrations exceeding 15% act as severe primary irritants, though no evidence of sensitization (allergic response) was observed.
  2. 02 Human patch testing on related salts demonstrates that concentrations below 3.0% are generally non-irritating, provided the formulation maintains a near-neutral pH.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

Because this ingredient is an industrial-strength surfactant often found in detergents, its inclusion in high-end skincare at very low levels (below 1%) may serve purely as a secondary emulsifier rather than a primary functional cleanser.


The Formula

Solubility
Both
Optimal pH 5.5 – 8
0 7 14

Stability

Maintains stability in hard water and standard conditions; however, it is highly sensitive to strong acids which can trigger hydrolysis or neutralization.

Synergies

  • Non-ionic surfactants
  • Isobutanol co-solvents

Conflicts

  • Cationic surfactants
  • Strong oxidizing agents
  • Strong acids

Safety

CIR Status
Safe as used
Max tested
4%
Pregnancy
Safe
Sensitization risk Low

Safe for cosmetic use specifically when formulated to be non-irritating. The primary risk is mechanical irritation at high concentrations or extreme pH levels.


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy High
Comedogenicity Low

Our Assessment

Questionable

An effective but aggressive surfactant that is better suited for industrial applications or rinse-off products than precision leave-on skincare.


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