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CALCIUM BEHENATE.

Valuable CAS 3578-72-1 / ANTICAKING, OPACIFYING, VISCOSITY CONTROLLING

A high-performance metallic soap and lipid-structuring agent that serves as a stabilizing backbone for anhydrous formulations. By creating a sophisticated crystalline network, it ensures the controlled release of oil-soluble actives while simultaneously delivering essential calcium ions to support the skin's structural integrity.

Viscosity controlling Barrier-repair signaling Opacifying agent Anticaking Emulsion stabilizer

Science

Calcium Behenate functions by establishing a rigid lipid matrix that increases the viscosity of oil phases and prevents the sedimentation of pigments or mineral filters. Biologically, it provides exogenous calcium to the stratum corneum—a critical signaling molecule that triggers keratinocyte differentiation (via KRT1 and KRT14 expression) and accelerates skin barrier repair.


Research

High confidence
Effective range 0.01–10%
Optimal

2.25%

Key findings

  1. 01 Demonstrated up-regulation of genes associated with cell differentiation and skin matrix synthesis when applied at 2.25% in barrier-repair formulations.
  2. 02 Proven efficacy as a stabilizing lubricant and gelling agent in pharmaceutical delivery systems at concentrations between 0.1% and 10%.
  3. 03 Identified as a synergistic agent that enhances antimicrobial preservation and texture stability in water-free balms at levels as low as 0.01%.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

While often used for texture at low levels, its primary biological benefits for skin barrier gene expression require a concentration of at least 2.25%. Formulations using it strictly as an opacifier below 0.1% are not leveraging its therapeutic potential.


The Formula

Solubility
Oil
Optimal pH 6.8 – 8.1
0 7 14

Stability

Highly stable in anhydrous (water-free) environments; however, it is sensitive to low pH environments which can cause the molecule to revert to behenic acid.

Synergies

  • Tribehenin
  • Biosurfactants
  • Mineral UV filters
  • Oil-soluble vitamins

Conflicts

  • Strong acids
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
22%
Pregnancy
Safe
Sensitization risk Low

The 2019 CIR assessment confirms safety up to 22%, though it is typically utilized at functional levels of 2-5% in high-end skincare.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A sophisticated dual-action ingredient that provides essential structural stability to formulas while actively promoting keratinocyte differentiation for a reinforced skin barrier.


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References