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Moumoujus

CALAMINE.

Valuable CAS 8011-96-9 / ABSORBENT, OPACIFYING, SKIN PROTECTING

Calamine is a time-tested medicinal mineral blend primarily composed of zinc oxide and a small percentage of ferric oxide. It serves as a multifunctional skin protectant and astringent, specifically utilized in precision skincare to manage inflammatory response and excess surface moisture.

Summary

soothing skin-protecting absorbent astringent

Science

Mechanism of Action

Calamine operates via three distinct pathways: it exerts a mild astringent effect to dry out surface exudates, creates a physical shield against environmental triggers, and induces an antipruritic cooling effect as its aqueous base evaporates from the skin surface.

Research

Clinical Evidence

High confidence
Effective range 8–25%
Optimal

8%

Key findings

  1. 01 Clinical evaluation demonstrates that an 8% concentration significantly reduces pruritus in contact dermatitis patients compared to placebo controls.
  2. 02 Recognized by the FDA OTC Monograph M016 for its efficacy in providing temporary relief from skin irritations and insect bites.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
5%
Red flag below
1%

While calamine is safe, it is frequently 'dusted' in formulations at low levels (<1%) simply to achieve a pink hue or for label claims. For therapeutic soothing and oil absorption, concentrations should ideally reach 8% or higher.

The Formula

Formulation

Solubility
Unknown
Optimal pH 6 – 7
0 7 14

Stability

Practically insoluble in both water and oil; must be formulated as a stable suspension. It remains stable under standard conditions but is sensitive to extreme thermal sublimation.

Synergies

  • Zinc Oxide
  • Bentonite
  • Glycerin

Conflicts

  • Mineral acids
  • Strong oxidizing agents
  • Highly alkaline ingredients

Safety

Safety Profile

CIR Status
Deferred to FDA
Max tested
25%
Pregnancy
Safe
Sensitization risk Low

Classified as a GRASE (Generally Recognized As Safe and Effective) Category I skin protectant by the FDA. The 25% limit aligns with SCCS safety assessments for its primary component, Zinc Oxide.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An exceptional ingredient for stabilizing oily and irritated skin profiles, provided it is used at therapeutic concentrations rather than for aesthetic coloring.

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