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C40-60 ALCOHOLS.

Valuable CAS 222400-19-3 / SKIN CONDITIONING, SURFACTANT - EMULSIFYING, VISCOSITY CONTROLLING

A group of ultra-long-chain fatty alcohols that serve as high-performance structural agents and skin-surface conditioners. These high-molecular-weight lipids are essential for creating sophisticated textures that provide lasting moisture retention and a smooth, refined skin feel.

emulsion stabilizing viscosity controlling skin conditioning occlusive

Science

They operate by organizing into structured lamellar gel networks—or liquid crystalline phases—when integrated with surfactants. This microscopic scaffolding stabilizes emulsions and increases viscosity, while simultaneously forming a breathable occlusive film on the skin that inhibits transepidermal water loss (TEWL).


Research

High confidence
Effective range 1.5–15%
Optimal

2.8%

Key findings

  1. 01 Clinical patch testing on human subjects (1.5%–5%) confirms a non-sensitizing and non-irritating profile.
  2. 02 In vivo evaluations demonstrate that concentrations between 2.8% and 14% significantly improve conditioning benefits and maintain formulation stability at temperatures exceeding 38°C.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

As a functional structuring agent rather than a marketing active, it is rarely 'dusted.' However, a concentration below 1% may indicate it is being used merely for minor thickening rather than for its advanced gel-network stabilizing properties.


The Formula

Solubility
Oil
Optimal pH 4 – 10
0 7 14

Stability

Extremely stable due to its saturated, non-ionic chemistry. Due to its high melting point of approximately 90°C, it requires high-temperature processing (90°C–105°C) for successful incorporation into the oil phase.

Synergies

  • Anionic surfactants
  • Non-ionic surfactants
  • High-polarity emollients

Conflicts

  • None; compatible across various surfactant systems.

Safety

CIR Status
Safe as used
Max tested
15%
Pregnancy
Safe
Sensitization risk Low

The CIR Expert Panel supports its safety in current cosmetic practices, noting its lack of irritation even in complex gel network phases.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional structural component for high-performance emulsions, providing both formulation integrity and superior barrier protection for dry and sensitive skin.


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