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C30-45 ALKYL DIMETHICONE.

Valuable CAS 243137-49-7 / SKIN CONDITIONING

A sophisticated silicone-based wax that bridges the gap between mineral waxes and liquid silicones to provide a breathable, semi-occlusive barrier. It creates a velvety structural matrix in formulations that enhances product stability while delivering a signature non-tacky, silky finish to the skin's surface.

Skin conditioning Viscosity controlling Emollient Film former

Science

This long-chain alkyl dimethicone functions by forming a flexible, water-resistant film that significantly inhibits trans-epidermal water loss (TEWL) without being comedogenic. Its unique molecular structure allows it to act as a coupling agent between silicone and organic oils, increasing the viscosity of the oil phase and ensuring a uniform distribution of active ingredients across the cutaneous barrier.


Research

High confidence
Effective range 1–15%
Optimal

5%

Key findings

  1. 01 A clinical Human Repeated Insult Patch Test (HRIPT) involving 83 participants confirmed that at a 5% concentration, the ingredient is a non-sensitizer and non-irritant.
  2. 02 Toxicological assessments of the pure substance (100% concentration) indicate an LD50 > 2000 mg/kg, classifying it as non-toxic with zero irritation potential in acute dermal exposure.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

As a structural wax and film-former, it is rarely 'dusted' because its primary value lies in its rheological impact; using it at microscopic levels would serve no functional purpose for the formula's texture or barrier performance.


The Formula

Solubility
Oil
Optimal pH 3 – 11
0 7 14

Stability

Requires hot processing as it has a melting point of 60-70°C. Once integrated into the oil or silicone phase, it enhances the thermal stability of emulsions.

Synergies

  • Hydrocarbon oils
  • Volatile silicones
  • UV filters (physical and chemical)

Conflicts

  • Highly polar water phases
  • Cold-process manufacturing

Safety

CIR Status
Safe as used
Max tested
15%
Pregnancy
Safe
Sensitization risk Low

Its high molecular weight prevents any significant dermal absorption, making it safe for long-term use. If used near the maximum 15% threshold in ocular products, specific irritation testing is advised.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional texture enhancer and barrier protector that provides the occlusion of a wax with the premium, breathable feel of a silicone.


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References