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C20-30 GLYCOL.

Valuable CAS 223239-98-3 / EMULSION STABILISING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

A high-molecular-weight aliphatic diol that functions as a sophisticated skin-conditioning agent and structural stabilizer. Its long-chain lipid structure provides a breathable, protective seal on the skin's surface to prevent dehydration without a heavy or greasy residue.

emollient skin conditioning emulsion stabilising occlusive

Science

It operates as an occlusive emollient by forming a thin, lipidic film over the stratum corneum. This barrier physically restricts trans-epidermal water loss (TEWL), effectively trapping moisture within the skin layers while simultaneously stabilizing the non-aqueous phase of emulsions to improve product texture and consistency.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical read-across assessments by the CIR indicate that longer-chain 1,2-glycols (C15-30) possess high lipophilicity and a molecular size that prevents deep dermal penetration, ensuring localized efficacy without systemic absorption.

Transparency

Not commonly dusted

As a structural and emollient ingredient rather than a primary bioactive, it is typically used for its physical properties; however, because it lacks a standard reported maximum concentration, it is rarely used in 'dusting' marketing claims.


The Formula

Solubility
Oil
Optimal pH 3 – 11
0 7 14

Stability

Extremely resilient across a wide pH spectrum and heat-stable with an estimated boiling point exceeding 400°C, making it ideal for high-temperature emulsion processing.


Safety

CIR Status
Safe as used
Pregnancy
Safe
Sensitization risk Low

The CIR Expert Panel supports its safety based on the ingredient's large molecular weight, which significantly limits skin penetration.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A highly stable and non-irritating emollient that excels at moisture retention and formula stabilization for all skin types.


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