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C18-30 GLYCOL.

Valuable CAS 223239-97-2 / EMULSION STABILISING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

A high-molecular-weight long-chain diol that acts as a robust moisture sealant and structural stabilizer in sophisticated skincare formulations. It excels at creating a breathable yet protective shield that mimics the lipid barrier, making it a cornerstone for intensive hydration and product longevity.

Emollient Occlusive Emulsion Stabilizer Viscosity Controller

Science

This ingredient functions through its unique molecular length (18 to 30 carbon atoms), which allows it to form a refined hydrophobic film atop the stratum corneum. This physical barrier significantly minimizes transepidermal water loss (TEWL) while simultaneously increasing the viscosity of the oil phase, ensuring a stable, homogenous emulsion that resists phase separation.


Research

Medium confidence
Effective range 0.5–5%
Optimal

2.5%

Key findings

  1. 01 Extrapolated safety data from 1,2-glycols demonstrate enhanced skin-penetration and humectancy.
  2. 02 Repeated Insult Patch Tests (RIPT) on analogous C15-18 glycols confirmed a lack of sensitization and irritation at concentrations up to 5%.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Because it primarily serves as a structural stabilizer and occlusive agent, using it below 0.5% often yields negligible benefits to the formula's texture or moisture-retention capabilities.


The Formula

Solubility
Oil
Optimal pH 3 – 11
0 7 14

Stability

Highly stable due to its saturated chemical structure; it is inert and resistant to hydrolysis across a broad pH spectrum.

Synergies

  • Humectants
  • Ceramides
  • Fatty Acids

Conflicts

  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Pregnancy
Safe
Sensitization risk Low

Classified as safe by the CIR Expert Panel (2011) due to its high molecular weight, which prevents deep systemic absorption.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptionally stable emollient that provides superior barrier protection and formula integrity for dry and sensitive skin profiles.


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