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C18-22 ISOALKYLAMIDOPROPYLETHYLDIMONIUM ETHOSULFATE.

Valuable / ANTISTATIC, HAIR CONDITIONING

A sophisticated cationic lipid analogue designed to restore the skin's protective F-layer. It functions as a biomimetic conditioning agent that significantly enhances the sensory profile and structural integrity of both skin and hair surfaces.

Skin conditioning Barrier repair Antistatic Texture enhancer

Science

This ingredient operates through electrostatic attraction; its positive charge allows it to bond firmly with the negatively charged proteins in our keratin. By mimicking 18-methyleicosanoic acid (18-MEA)—the primary natural lipid of our skin's barrier—it deposits a microscopic, hydrophobic film that smooths the stratum corneum, reduces friction, and prevents transepidermal water loss.


Research

High confidence
Effective range 0.03–5%
Optimal

1.5%

Key findings

  1. 01 Demonstrated up to 95% reduction in surface friction and combing force in hair fiber analysis.
  2. 02 Proven to significantly enhance post-rinse 'wet skin feel' in cleansing formulations at concentrations as low as 0.03%.
  3. 03 Increases surface luster and reflectivity by up to 75.4% through lipid layer restoration.

Transparency

Not commonly dusted
Min. effective
0.03%
Red flag below
0.01%

Because this ingredient is effective at exceptionally low concentrations (0.03%) for sensory improvement, it is rarely 'dusted.' However, for restorative barrier benefits, we look for inclusions closer to 1% or higher.


The Formula

Solubility
Water
Optimal pH 3 – 7.5
0 7 14

Stability

Maintains peak performance in acidic environments (pH 3.5–5.5) where its cationic charge is most potent. Often pre-dispersed in glycols for better cold-process integration.

Synergies

  • Glycerin
  • Fatty alcohols
  • Non-ionic surfactants

Conflicts

  • Anionic surfactants (SLS/SLES)
  • Carbomer
  • Xanthan Gum
  • Strong oxidizers

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Its high molecular weight ensures it remains on the surface of the skin, preventing systemic absorption and minimizing irritation potential.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-precision biomimetic lipid that provides immediate sensory smoothing while reinforcing the skin's long-term moisture barrier.


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