Science
Mechanism of Action
This amphiphilic molecule features a hydrophilic head and a lipophilic tail, allowing it to integrate seamlessly into the stratum corneum's lipid bilayer. It works by filling gaps within intercorneocyte clusters, effectively sealing the skin barrier to minimize transepidermal water loss (TEWL) while acting as a stabilizer at the oil-water interface in emulsions.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 A 2012 CIR Final Report concluded that 1,2-glycols, including C15-18, exhibit a very low order of toxicity with an LD50 exceeding 20.0 g/kg.
- 02 Structural modeling from 2011 indicates that the longer-chain length of C15-18 Glycol results in significantly lower skin penetration compared to shorter-chain glycols, enhancing surface-level barrier protection.
Transparency
Dusting Analysis
As a functional emollient and viscosity regulator, C15-18 Glycol is rarely used as a 'marketing' ingredient; it is typically included at functional levels to achieve specific textural and barrier-repair benchmarks.
The Formula
Formulation
Stability
Exceptionally stable across a broad pH range and thermally resilient with high boiling points, making it suitable for hot-process emulsions.
Synergies
- Ceramides
- Squalane
- UV Filters
Safety
Safety Profile
The CIR Expert Panel considers it safe for cosmetic use; its low penetration profile makes it an ideal candidate for sensitive skin and pregnancy-safe formulations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An excellent multi-functional ingredient that provides reliable barrier support and emulsion stability with a superior safety and irritation profile.
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