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Ingredient directory

C14-20 Isoalkylamidopropylethyldimonium Ethosulfate

A sophisticated cationic quaternary ammonium compound designed for high-performance surface modification. It functions as a substantive conditioning agent that establishes a microscopic, breathable film to restore the tactile quality and barrier integrity of compromised skin and hair fibers.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

antistatic hair conditioning skin conditioning barrier reinforcement

Science

This molecule utilizes a strong positive (cationic) charge to magnetically adhere to negatively charged surfaces, which are more prevalent on damaged skin and hair. Once bonded, it creates a uniform, lubricious lipid-like layer that neutralizes static electricity, significantly reduces surface friction, and reinforces the epidermal moisture barrier to prevent transepidermal water loss.


Research

High confidence
Effective range 1–3%
Optimal

2%

Key findings

  1. 01 Application at 1-3% demonstrated superior manageability and sensory improvement on textured (Type 3/4) and chemically damaged hair compared to traditional quaternary salts.
  2. 02 At a 1% concentration, the ingredient effectively deposits a substantive film that enhances skin softness and barrier function without leaving a greasy or heavy residue.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

To achieve the characteristic 'substantive' barrier effect and manageability improvements shown in clinical trials, a minimum concentration of 1% is typically required. Formulas using significantly less may be including it for marketing 'claims' rather than functional performance.


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Maintains stability and efficacy within the acidic to neutral range; however, it becomes unstable and loses performance in alkaline environments exceeding pH 8.5.

Synergies

  • Non-ionic surfactants
  • Glycerin
  • Cationic polymers

Conflicts

  • Anionic surfactants (SLS/SLES) as they form insoluble complexes
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Reviewed and cleared by the CIR as part of the Alkylamidoalkyl Dialkylamines group. It is non-irritating and safe for leave-on applications up to its maximum tested levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional conditioning agent for repairing the physical feel and moisture-retention capabilities of damaged skin and multi-cultural hair types.


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