Science
Mechanism of Action
Functions through amphiphilic molecular structure where the lipophilic C12-13 carbon chain binds to oils and sebum while the hydrophilic polyethylene glycol head interacts with water, reducing interfacial tension to facilitate oil removal and create stable emulsions
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Clinical evaluation in 6,202 patients demonstrated low sensitization rates with only 1.77% weakly positive and 0.34% strongly positive allergic reactions
Transparency
Dusting Analysis
As a functional surfactant and emulsifier, this ingredient serves essential formulation purposes rather than acting as filler material
The Formula
Formulation
Stability
Maintains stability across normal cosmetic pH ranges and demonstrates compatibility with anionic, cationic, and other non-ionic surfactants due to its non-ionic nature
Synergies
- other non-ionic surfactants
- anionic surfactants
- cationic surfactants
Conflicts
- strong oxidizing agents
- strong acids
Safety
Safety Profile
Approved for use when properly formulated to minimize irritation; manufacturers must monitor for trace 1,4-dioxane from ethoxylation process
Your Skin
Skin Compatibility
Our Assessment
Verdict
A well-tolerated, versatile surfactant suitable for multiple skin types with established safety data and broad formulation compatibility.
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References
Sources