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Moumoujus

BUTYRALDEHYDE.

Questionable CAS 123-72-8 / PERFUMING

Butyraldehyde is a volatile aldehyde compound primarily employed as a fragrance component in cosmetic formulations, delivering distinctive pungent, fruity, or green aromatic notes. While contributing no therapeutic skin benefits, this ingredient carries notable sensitization risks and requires careful regulatory compliance. Its volatile nature and potential for oxidative degradation present formulation challenges that limit its practical application in precision skincare.

Summary

fragrance

Science

Mechanism of Action

Functions purely as a volatile fragrance molecule with no direct skin action, but can undergo chemical reaction with epidermal proteins to form hapten complexes, potentially triggering contact sensitization responses in susceptible individuals

Research

Clinical Evidence

Medium confidence
Effective range 0.17–5%
Optimal

N/A

Key findings

  1. 01 Safety threshold established for IFRA Category 1 applications to minimize skin sensitization risk
  2. 02 Maximum allowable concentration in specific consumer fragrance categories

Transparency

Dusting Analysis

Not commonly dusted

Not a dustable ingredient - primarily regulated fragrance component with established IFRA concentration limits

The Formula

Formulation

Solubility
Both
Optimal pH 6 – 7
0 7 14

Stability

Exhibits high volatility and air sensitivity with tendency to oxidize into butyric acid; requires sealed storage with protection from heat and light exposure

Conflicts

  • strong oxidizing agents
  • strong acids
  • strong bases
  • strong reducing agents

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
5%
Sensitization risk High

Classified as skin sensitizer and serious eye irritant under GHS H319; regulated under IFRA standards with category-specific concentration limits

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

High sensitization risk and lack of skin benefits make this fragrance component unsuitable for precision skincare applications.

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