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BUTYLGLUCOSIDE CAPRATE.

Valuable CAS 134932-39-1 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A sophisticated non-ionic surfactant and penetration enhancer that excels at creating stable nanoemulsions for superior active ingredient delivery. This alkyl glucoside derivative combines gentle cleansing properties with sebum-regulating benefits, making it particularly valuable in oil-control and acne treatment formulations. Its dual amphiphilic nature allows it to function effectively across both water and oil phases while maintaining excellent skin compatibility.

surfactant penetration enhancer emulsifier sebum regulator skin conditioner

Science

Functions as an amphiphilic lipid that reduces interfacial tension to create stable nanoemulsions with oil globules smaller than 100nm. This nano-scale architecture facilitates enhanced transport of active ingredients through the stratum corneum barrier. Additionally, it provides sebum regulation through mild modulation of sebaceous gland activity and acts as a hydrotrope to improve solubility of lipophilic actives.


Research

High confidence
Effective range 0.1–2%
Optimal

1%

Key findings

  1. 01 Significantly enhanced penetration of active principles into skin surface layers when formulated in nanoemulsions with droplet sizes below 100nm
  2. 02 Demonstrated effective stabilization of fragrance solutions and improved active delivery in leave-on applications

Transparency

Not commonly dusted

As a functional surfactant and penetration enhancer with established efficacy data, this ingredient is typically used at meaningful concentrations rather than trace amounts for marketing purposes.


The Formula

Solubility
Both
Optimal pH 2 – 9
0 7 14

Stability

Maintains stability during thermal storage from 0°C to 45°C. Clear microemulsion or nanoemulsion formulations typically require pH above 6.5 for optimal transparency.

Synergies

  • Lipophilic actives (improved solubility)
  • Nanoemulsion systems
  • Sebum-regulating compounds

Conflicts

  • Strongly acidic environments (risk of hydrolysis)
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
2%
Pregnancy
Safe
Sensitization risk Low

Evaluated as part of Alkyl Glucosides group assessment. CIR Expert Panel confirmed safety when formulated to avoid irritation.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A multifunctional ingredient that delivers proven penetration enhancement and sebum regulation with excellent safety profile across all skin types.


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