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BUTYL ANGELATE.

Valuable CAS 7785-64-0 / PERFUMING

A naturally-derived ester that functions as both a gentle skin-conditioning agent and subtle fragrance component. This compound demonstrates notable anti-inflammatory properties through its interaction with cellular pathways, making it particularly suitable for sensitive skin formulations.

Skin conditioning Fragrance Anti-inflammatory Antioxidant

Science

Functions as a thiol-acceptor molecule, potentially undergoing Michael addition reactions with biological thiols to modulate inflammatory pathways. Additionally contributes antioxidant activity by neutralizing reactive oxygen species (ROS) and provides skin-conditioning benefits through its ester structure.


Research

Medium confidence
Effective range 0.29–3%
Optimal

1%

Key findings

  1. 01 Accelerated wound healing in diabetic rats with 84.21% wound contraction after 14 days when used in Helichrysum italicum essential oil
  2. 02 Faster soothing of UV-irradiated skin in Roman chamomile oil formulations compared to control groups

Transparency

Not commonly dusted

Not commonly used as a dusting ingredient due to its primary function as a fragrance and conditioning agent rather than an active


The Formula

Solubility
Oil
Optimal pH 5 – 8.5
0 7 14

Stability

Stable in neutral to alkaline conditions but susceptible to hydrolysis below pH 5.0

Synergies

  • Essential oils
  • Other ester compounds
  • Antioxidant systems

Conflicts

  • Strong acids
  • Strong bases
  • Oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
3%
Pregnancy
Safe
Sensitization risk Low

RIFM-approved for current use levels, classified as Cramer Class I (low oral toxicity), FDA FEMA GRAS status for food use


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A well-tolerated multifunctional ingredient that combines gentle conditioning with anti-inflammatory benefits, suitable for all skin types including sensitive skin.


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