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Ingredient directory

Buttermilk Extract Powder

A bioactive powder derived from buttermilk that delivers sphingolipids, lactic acid, and milk proteins to strengthen skin barrier function and provide gentle conditioning. This multifunctional ingredient combines the exfoliating benefits of natural alpha-hydroxy acids with barrier-replenishing phospholipids and ceramide precursors. Clinical research demonstrates its ability to enhance filaggrin expression and maintain hyaluronic acid synthesis while offering protection against photoaging.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

skin conditioning hair conditioning barrier repair mild exfoliation

Science

Functions through multiple pathways including mild enzymatic exfoliation via lactic acid content, lipid barrier restoration through milk sphingolipids and glucocerebrosides that stimulate endogenous ceramide production, and skin conditioning via film-forming proteins that enhance moisture retention and aquaporin-3 expression.


Research

Medium confidence
Effective range 1–5%
Optimal

1%

Key findings

  1. 01 1% concentration significantly improved skin barrier recovery and increased filaggrin and aquaporin-3 expression while maintaining hyaluronic acid levels (MDPI, 2020)
  2. 02 Buttermilk concentrated powder suppressed UVB-induced oxidative stress and inhibited collagen-degrading enzymes while stimulating procollagen type I synthesis (PMC/NIH, 2022)

Transparency

Not commonly dusted

Not commonly used for dusting purposes due to legitimate barrier repair and conditioning benefits with established clinical support


The Formula

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Maintains optimal stability in slightly acidic environments that preserve protein integrity and lipid component functionality

Synergies

  • ceramides
  • hyaluronic acid
  • other milk-derived proteins

Conflicts

  • prolonged high heat exposure above 60°C
  • highly alkaline formulations above pH 8.0

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

FDA recognizes as GRAS with established safety profile under CIR assessment for milk-derived ingredients; can be used up to 100% in wash-off applications


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A well-researched multifunctional ingredient that effectively combines barrier repair, gentle exfoliation, and conditioning benefits with excellent safety profile.


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