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BUTOXYHYDROXYPROPYL CETYL HYDROXYETHYLCELLULOSE.

Valuable CAS 942427-44-3 / EMULSION STABILISING, VISCOSITY CONTROLLING

A sophisticated hydrophobically modified cellulose polymer that functions as both an emulsion stabilizer and film-forming agent. This dual-action ingredient creates a breathable protective barrier on skin while enhancing moisture retention without relying on traditional surfactants. Its unique molecular structure makes it particularly effective in ceramide-based formulations for barrier repair.

Emulsion stabilizer Film former Viscosity controller Moisture barrier enhancer

Science

Functions through its amphiphilic structure where the hydrophilic cellulose backbone remains in the water phase while hydrophobic cetyl and butoxy chains anchor into oil droplets and skin lipids. This creates stable emulsions and forms a permeable film that reduces transepidermal water loss while allowing skin to breathe naturally.


Research

Medium confidence
Effective range 0.1–1%
Optimal

0.5%

Key findings

  1. 01 Demonstrated significant reduction in transepidermal water loss when used to stabilize pseudo-ceramides in barrier repair formulations

Transparency

Not commonly dusted

As a functional polymer used at specific concentrations for emulsion stability, dusting is not applicable to this ingredient


The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Maintains stability across pH 2-12 but performs optimally for texture between pH 5.0-7.0. Offers superior electrolyte tolerance compared to carbomer-based systems.

Synergies

  • Ceramides
  • Pseudo-ceramides
  • Barrier repair actives

Conflicts

  • High concentrations of divalent salts
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
2%
Pregnancy
Safe
Sensitization risk Low

Large molecular weight prevents skin penetration. Non-irritating and non-sensitizing with excellent safety profile.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A highly functional polymer that excels at creating stable, skin-compatible formulations with proven barrier enhancement properties.


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