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BUTENEDIOL.

Questionable CAS 110-64-5 / NOT REPORTED

An unsaturated diol solvent that enhances the delivery and solubility of active ingredients in skincare formulations. Unlike its saturated counterpart butylene glycol, butenediol contains a reactive double bond that makes it more suitable as a formulation intermediate than a standalone active ingredient.

solvent humectant

Science

Functions as a polar co-solvent and humectant, improving the penetration of active compounds while drawing moisture to the skin surface. The unsaturated double bond structure allows for enhanced solubilization of both hydrophilic and lipophilic ingredients within the formulation matrix.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Primarily used as an industrial intermediate rather than a cosmetic active, making dusting practices uncommon in consumer skincare products.


The Formula

Solubility
Water
Optimal pH 5 – 7.5
0 7 14

Stability

Remains stable at room temperature but the unsaturated double bond creates vulnerability to oxidative degradation when exposed to strong oxidizing agents or halogens.

Conflicts

  • Strong oxidizing agents
  • Strong reducing agents
  • Acid chlorides
  • Acid anhydrides
  • Chloroformates
  • Isocyanates

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Classified as Category 2 skin and eye irritant by ECHA and GHS. Regulated as industrial chemical with restrictions in some jurisdictions due to potential conversion to controlled substances.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Questionable

Limited cosmetic application due to moderate irritancy and primary role as industrial intermediate rather than proven skincare active.


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