Science
Mechanism of Action
Functions through four primary pathways: scavenges free radicals via phenolic and flavonoid compounds, inhibits inflammatory mediators including COX enzymes and cytokines IL-6 and TNF-alpha, replenishes skin lipids through oleic and linoleic acid content, and modifies stratum corneum fluidity to enhance active ingredient absorption.
Research
Clinical Evidence
Medium confidence5%
Key findings
- 01 10% w/w topical application increased wound tensile strength by 40.84% in rodent models
- 02 1% standardized extract demonstrated cytokine downregulation in cell cultures
- 03 5-10% concentration enhanced transdermal permeation without active degradation
Transparency
Dusting Analysis
Limited commercial adoption and specialized sourcing requirements make dusting unlikely for this botanical extract.
The Formula
Formulation
Stability
Requires antioxidant protection due to high unsaturated fatty acid content; tocopherol or BHT recommended for oil-based formulations to prevent oxidation
Synergies
- Vitamin E
- BHT
- other antioxidants
Conflicts
- strong oxidizing agents
- highly alkaline compounds
Safety
Safety Profile
Generally well-tolerated but potential cross-reactivity exists for individuals allergic to Anacardiaceae family members (cashews, mangoes, poison ivy)
Your Skin
Skin Compatibility
Our Assessment
Verdict
A versatile botanical with solid research backing, though limited commercial precedent and potential allergenicity require careful consideration.
Related
Similar Ingredients
Finding similar ingredients…