Science
Mechanism of Action
Forms stable, negatively charged complexes with basic amino acid residues in proteins, particularly arginine and aromatic amino acids, allowing for selective binding to skin proteins and membranes while functioning as a pH-sensitive indicator dye.
Research
Clinical Evidence
Medium confidence0.05%
Key findings
- 01 Ophthalmic safety study at 0.2% showed no toxicity or tissue abnormalities in porcine eyes
- 02 Cell culture studies at 0.05% demonstrated no inhibition of cell proliferation or toxic effects on retinal epithelium
Transparency
Dusting Analysis
Primarily used as a specialized colorant and pH indicator rather than an active skincare ingredient, making dusting practices irrelevant for this compound.
The Formula
Formulation
Stability
Stable in aqueous and alcoholic solutions under normal conditions but exhibits concentration-dependent color changes and sensitivity to oxidation-reduction environments.
Conflicts
- strong oxidizing agents
- cationic surfactants
- strong reducing agents
Safety
Safety Profile
Related compound Tetrabromophenol Blue approved by SCCS for hair dye use at 0.2% maximum concentration on scalp.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Limited skincare-specific research despite established safety profile in related applications.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources