Science
Mechanism of Action
Sulforaphane activates the Nrf2 signaling pathway, triggering production of endogenous Phase 2 detoxification enzymes that neutralize free radicals and reduce oxidative stress. Simultaneously inhibits collagen-degrading MMP-1 enzymes and suppresses pro-inflammatory cytokines to maintain skin structural integrity.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 37% reduction in UV-induced erythema with 2.5-10% broccoli sprout extract (PNAS/Johns Hopkins)
- 02 Significant increase in Type I procollagen and MMP-1 inhibition in human fibroblasts at 25-100 mg/mL (Int J PharmTech Research, 2016)
Transparency
Dusting Analysis
Effective concentrations start at 2.5%, making sub-1% concentrations likely insufficient for meaningful biological activity
The Formula
Formulation
Stability
Heat-sensitive above 40°C due to sulforaphane thermolability. Requires protection from light and air exposure to prevent antioxidant degradation.
Synergies
- Vitamin E
- Vitamin C
- other antioxidants
Conflicts
- high-heat processing
- strong alkaline conditions above pH 7.5
- prolonged UV exposure
Safety
Safety Profile
GRAS status based on food-grade safety profile. Typical skincare usage ranges 1-3% for pure extracts.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A scientifically-validated botanical with proven cellular defense activation and photoprotective benefits at clinically meaningful concentrations.
Related
Similar Ingredients
Finding similar ingredients…