Science
Mechanism of Action
Rich in Gamma-Linolenic Acid (GLA), it converts to DGLA, a precursor to anti-inflammatory PGE1, and inhibits leukotriene synthesis. It restores stratum corneum lipids, boosts ceramide 1 and filaggrin, and helps normalize skin pH, thus enhancing barrier function and hydration.
Research
Clinical Evidence
Medium confidence0.5%
Key findings
- 01 Significantly decreased melasma and showed visible skin brightening after 6 and 8 weeks in an 8-week clinical trial with 21 women.
- 02 Effective in reducing irritation and/or stinging caused by hydroxy acids and/or retinoids.
- 03 Normalized skin barrier function and reduced inflammation in infants and children with seborrheic or atopic dermatitis.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Hydrogenation enhances stability, but proper storage in cool, dry, sealed conditions away from light is crucial to prevent oxidation and rancidity. It should be incorporated into the oil phase of emulsions or anhydrous formulations.
Synergies
- Reduces irritation from hydroxy acids and retinoids
Safety
Safety Profile
While generally well-tolerated, source borage oil must be certified pyrrolizidine alkaloid (PA)-free to avoid hepatotoxic risks. Oral borage oil is contraindicated during pregnancy, though specific topical ester safety in pregnancy is not detailed.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This versatile ingredient is essential for comprehensive skin health, offering significant barrier support, anti-inflammatory effects, and visible brightening while minimizing irritation.
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