Science
Mechanism of Action
Bletilla striata contains polysaccharides that enhance hydration and barrier repair, while glycoproteins stimulate cell turnover and collagen production. It reduces inflammation by inhibiting inflammatory factors, and exhibits antioxidant and anti-tyrosinase activities for improved skin health.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 In vitro and 3D epidermal skin model studies indicate soothing effects on inflammation and promotion of skin barrier repair.
- 02 In vitro studies demonstrate anti-tyrosinase activity with a maximum inhibition of 53.69%, suggesting skin whitening potential.
- 03 In vitro and non-human in vivo evaluations showed wound-healing properties with 0.5-2% Bletilla striata Polysaccharide (BSP) in hydrogels.
- 04 Chloroform subfractions from ethanol extracts exhibited strong antioxidant (free radical-scavenging) activity with an IC50 of 0.848 mg/L.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Bletilla striata Polysaccharide (BSP) lacks biostability on its own and requires combination with other polymers, such as methylcellulose, to enhance stability for medical applications.
Synergies
- Other polymers (e.g., methylcellulose) for enhanced stability
Safety
Safety Profile
Human safety and efficacy studies for topical application are limited. Rare allergic dermatitis has been reported with internal use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While in vitro and 3D epidermal model studies show promise for hydration, soothing, and anti-aging, comprehensive human clinical efficacy and safety data remain limited.
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References
Sources