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BIS-CETEARYL AMODIMETHICONE.

Valuable CAS 1126942-72-0 / HAIR CONDITIONING

A sophisticated, amino-modified silicone polymer designed to provide superior surface refinement and structural barrier support. It creates an ultra-thin, breathable matrix that smooths micro-relief while maintaining essential gas exchange for the skin.

Skin conditioning Film forming Barrier protection Texture refinement

Science

This ingredient utilizes positively charged nitrogen atoms within its amino groups to create a 'substantive' bond with the skin’s naturally negative surface. This ionic attraction allows the molecule to form a durable, hydrophobic, and viscoelastic film that prevents trans-epidermal water loss (TEWL) and shields against environmental particulate matter without a heavy or greasy residue.


Research

High confidence
Effective range 1–10%
Optimal

2%

Key findings

  1. 01 Clinical evaluation of anti-aging serums containing 2% Bis-Cetearyl Amodimethicone demonstrated a 13.4% reduction in measured skin roughness through barrier reinforcement.
  2. 02 Safety and performance data from the CIR Final Report indicate that modified amodimethicones at 1-10% effectively minimize the appearance of fine lines by forming a protective, light-refracting film.

Transparency

Commonly dusted
Min. effective
1.5%
Red flag below
0.5%

While often used at sub-1% levels to provide a silky 'marketing' feel, clinical data suggests a minimum of 2% is required to achieve measurable improvements in skin texture and barrier protection.


The Formula

Solubility
Oil
Optimal pH 3 – 7
0 7 14

Stability

Optimal stability is achieved in acidic to neutral environments. It is frequently formulated as a non-ionic emulsion to facilitate integration into the aqueous phase of oil-in-water systems.

Synergies

  • Humectants
  • Non-ionic emulsifiers
  • Occlusive lipids

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Strong alkalis

Safety

CIR Status
Safe as used
Max tested
15%
Pregnancy
Safe
Sensitization risk Low

With a high molecular weight, this ingredient is not absorbed into the bloodstream. Toxicity studies show an LD50 greater than 2000 mg/kg, confirming its excellent safety profile for topical use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptionally effective film-former for barrier repair and texture refinement, provided it is used at therapeutic concentrations above 1%.


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