Science
Mechanism of Action
Utilizing a cationic (positively charged) framework, this molecule selectively adheres to damaged, negatively charged sites on the skin and hair. By replicating the natural 18-MEA lipid, it restores essential hydrophobicity and reinforces the physical barrier, significantly lowering transepidermal water loss and smoothing the surface texture.
Research
Clinical Evidence
High confidence2.5%
Key findings
- 01 In vivo testing showed that concentrations between 1.0% and 5.0% significantly improved skin barrier integrity and reduced TEWL via lipid layer supplementation.
- 02 A 0.6% concentration successfully restored hydrophobic properties to damaged keratinous surfaces, improving texture and combability.
Transparency
Dusting Analysis
While it provides hair-smoothing benefits at 0.6%, therapeutic skin barrier repair requires at least 1.0%. Formulations including this ingredient for barrier claims at trace levels (below 0.5%) are likely 'dusting' for label appeal.
The Formula
Formulation
Stability
Highly stable in aqueous solutions and emulsions, particularly in slightly acidic environments.
Synergies
- Ceramides
- Fatty acids
- Non-ionic emulsifiers
Conflicts
- High concentrations of strong anionic surfactants (precipitation risk)
- Strongly alkaline conditions (protein degradation)
Safety
Safety Profile
Classified as a safe hydrolyzed protein derivative; quaternary ammonium structure is non-sensitizing at cosmetic use levels.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An exceptional biomimetic ingredient for restoring the skin's lipid defense and hair's structural integrity, provided it is used at clinical concentrations.
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