Science
Mechanism of Action
This ingredient functions as a hydrophobically modified ethoxylated urethane (HEUR). It builds a reversible three-dimensional network within a formula by anchoring its hydrophobic C16-20 isoalkoxy end-caps to oil droplets or surfactants, providing exceptional viscosity control and a protective, non-occlusive film on the skin.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 A Human Repeat Insult Patch Test (HRIPT) involving a 30% concentration confirmed the polymer is a non-sensitizer and causes zero irritation to human skin.
- 02 In vitro toxicity evaluations using the EpiDerm™ Skin Model at 30% concentration showed no significant impact on epidermal keratinocyte viability, predicting high biocompatibility.
Transparency
Dusting Analysis
As a structural rheology modifier, this ingredient is typically used at functional levels to ensure formula stability; however, it is not an 'active' in the traditional sense, so dusting is less relevant than its impact on emulsion stability.
The Formula
Formulation
Stability
Exhibits remarkable stability across an extreme pH range and maintains consistent viscosity even in high-electrolyte environments or elevated temperatures. It is compatible with cold-process manufacturing.
Synergies
- Anionic surfactants
- Non-ionic surfactants
- Cationic conditioning agents
Conflicts
- None reported
Safety
Safety Profile
With a molecular weight exceeding 7,000 Daltons, this polymer is too large to penetrate the skin barrier, ensuring it remains localized on the surface. Residual HDI monomers are maintained at ultra-low levels below 1 ppm.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An exceptionally safe and robust rheology modifier that provides superior texture and stability to high-performance skincare and cosmetic formulas.
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