Science
Mechanism of Action
By integrating long-chain alkyl groups (C10-28) onto a silicone backbone, this molecule anchors itself to the skin's lipid matrix. It forms a vapor-permeable, hydrophobic shield that prevents transepidermal water loss (TEWL) while significantly improving the glide and spreadability of topical formulations.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Clinical assessments by the CIR (2021) demonstrate that concentrations up to 15% effectively strengthen the skin barrier via a non-absorptive, breathable film.
- 02 A 2003 repeated insult patch test on 83 subjects confirmed that a 5.0% concentration is both non-sensitizing and non-irritating to human skin.
Transparency
Dusting Analysis
Typically used as a structural or conditioning agent, its benefits in barrier repair and texture are usually realized at concentrations above 1%. Levels below 0.5% in barrier creams may indicate it is being used only for label claims or minor slip enhancement.
The Formula
Formulation
Stability
Exhibits exceptional thermal and oxidative stability. Unlike standard dimethicone, its alkyl modification allows for superior blending with natural vegetable oils and botanical waxes.
Synergies
- Vegetable oils
- Natural waxes
- Pigment dispersions
Conflicts
- Strong oxidizing agents
Safety
Safety Profile
The large molecular weight of this polymer prevents skin penetration, making it toxicologically inert. It is considered safe for all leave-on applications, though caution is advised for airbrush-delivered products.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance conditioning agent that provides a superior skin-feel and breathable protection for compromised skin barriers.
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References
Sources