Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

BIOSACCHARIDE GUM-1.

Valuable CAS 194237-89-3 / SKIN CONDITIONING

A high-performance anionic polysaccharide obtained via bacterial fermentation that provides a unique 'touch' and multi-sensory experience. It acts as a biological soothing agent and long-term hydrator, creating a breathable, protective film that restores skin comfort and barrier integrity.

Summary

Soothing Moisturizing Skin Conditioning Anti-Aging

Science

Mechanism of Action

This ingredient operates through a triple-action biological pathway: it inhibits ASIC receptors to block the release of inflammatory Substance P (soothing), forms a non-occlusive water-binding film (moisturizing), and stimulates the 'longevity protein' Sirtuin-1 to accelerate cellular renewal and barrier repair.

Research

Clinical Evidence

High confidence
Effective range 1–5%
Optimal

3%

Key findings

  1. 01 At a 3% concentration, in vivo testing demonstrated a 47% reduction in neuro-sensory tingling sensations on skin irritated by lactic acid.
  2. 02 A 1% concentration showed a delayed but superior moisturizing effect compared to Hyaluronic Acid after the 3-hour mark, maintaining parity at 8 hours.
  3. 03 Ex-vivo studies at 1% confirmed stimulation of Sirtuin-1, promoting enhanced keratinocyte differentiation and structural barrier restructuring.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
1%
Red flag below
0.5%

While often included for its 'slip' and texture-enhancing properties at low levels, clinical benefits for sensitivity and Sirtuin-1 activation require at least 1%. Formulas using it below 1% are likely leveraging it for marketing claims or basic viscosity rather than precision repair.

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 10
0 7 14

Stability

Remarkably stable across a wide pH spectrum. While it can withstand temperatures up to 75°C briefly, it is best incorporated during the cooling phase below 45°C to maintain structural integrity.

Synergies

  • Hyaluronic Acid (for immediate and sustained hydration layers)
  • Lactic Acid (to mitigate sensory irritation from AHAs)

Conflicts

  • Cationic surfactants
  • Cationic polymers (Polyquaternium-10)
  • High concentrations of divalent cations (may cause precipitation)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
6%
Pregnancy
Safe
Sensitization risk Low

Reviewed by the CIR in 2016 and deemed safe for leave-on cosmetic applications; the maximum reported industry usage is 6%.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An exceptional precision ingredient for sensitive skin that bridges the gap between immediate sensory relief and long-term barrier longevity.

Related

Similar Ingredients

Finding similar ingredients…

References

Sources