Science
Mechanism of Action
Operates as a bioactive metabolite delivery system, providing the skin with a concentrated blend of lactic acid, peptides, and exopolysaccharides. These compounds upregulate structural proteins, specifically Occludin and Desmocollin 1, to fortify cellular junctions while stimulating the production of endogenous antimicrobial peptides to maintain microbiome equilibrium.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 In-vivo studies at 5.0% demonstrated a 47% reduction in skin redness and notable antimicrobial activity against C. acnes.
- 02 Concentrations of 1.0% have been shown to facilitate skin barrier repair via DNA repair enzyme pathways.
- 03 A 2.0-5.0% range is clinically validated to improve the velocity and quality of epidermal growth for enhanced barrier integrity.
Transparency
Dusting Analysis
Due to the marketing appeal of 'probiotic' ingredients, this ferment is frequently included at negligible concentrations (<0.5%). While 1.0% provides baseline repair, clinical data suggests that a 5.0% concentration is necessary to achieve significant anti-redness and antimicrobial benefits.
The Formula
Formulation
Stability
Thermolabile; must be incorporated during the cooling phase of formulation at temperatures below 40°C. Naturally stable against microbial growth due to inherent bacteriocins.
Synergies
- Prebiotics
- Ceramides
- Niacinamide
- Hyaluronic Acid
Conflicts
- Strong oxidizing agents
- Strong acids/bases
- Processing temperatures exceeding 50°C
Safety
Safety Profile
Reviewed by the CIR Expert Panel in 2024; found to be non-genotoxic and non-irritating in human patch testing.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An essential multi-functional postbiotic for microbiome health and barrier fortification, particularly effective for sensitive or reactive skin when used at 5%.
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References
Sources