Science
Mechanism of Action
This filtrate operates by stimulating the expression of essential barrier proteins, including filaggrin, loricrin, and involucrin, alongside the upregulation of Aquaporin-3 to optimize water transport. It actively scavenges reactive oxygen species (ROS), promotes DNA repair mechanisms following UV exposure, and suppresses pro-inflammatory cytokines such as TNF-α and IL-8 to soothe reactive skin.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 A 1.0% concentration demonstrated a 20.62% reduction in transepidermal water loss (TEWL) and a 21.01% decrease in erythema over 28 days.
- 02 Application at 10.0% significantly improved barrier function and lowered sensitivity thresholds in reactive skin types.
- 03 Dose-dependent antioxidant activity (2.0-10.0%) successfully inhibited UVA-induced oxidative stress and intracellular damage.
Transparency
Dusting Analysis
While beneficial at low levels, many formulations include this ingredient at negligible concentrations (under 0.5%) for marketing purposes. To achieve measurable barrier repair and redness reduction, a minimum of 1.0% is clinically required.
The Formula
Formulation
Stability
Thermolabile; must be incorporated during the cooling phase (below 40°C) to preserve metabolite bioactivity. Requires protection from direct light and atmospheric oxygen.
Synergies
- Ceramides
- Hyaluronic Acid
- Niacinamide
Conflicts
- High pH environments (>7.0)
- Strong oxidizing agents
- Concentrated acidic exfoliants (direct mixing)
Safety
Safety Profile
Generally recognized as safe (GRAS) for topical application. It is clinically regarded as non-irritating and suitable for long-term use in leave-on repair products.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance postbiotic essential for fortifying the skin barrier and mitigating UV-induced oxidative stress.
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References
Sources