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BICYCLOPENTYLONE.

Optional CAS 4884-24-6 / PERFUMING

Bicyclopentylone is a specialized aromatic ketone frequently utilized in precision skincare for its complex olfactory profile and masking capabilities. Often identified as a phytochemical marker in lemongrass, it provides formulations with a sophisticated blend of fruity-green and woody notes while contributing secondary antimicrobial support.

perfuming masking antimicrobial support

Science

Primarily serving as a sensory enhancer, Bicyclopentylone interacts with olfactory receptors to mask base ingredient odors through its volatile aromatic structure. Beyond fragrance, it functions as a component of plant-derived defensive systems, exhibiting mild inhibitory effects against specific bacterial strains like S. aureus and acting as a volatile repellent by disrupting the chemical attraction signals used by insects.


Research

Medium confidence
Effective range 0.05–2%
Optimal

1%

Key findings

  1. 01 Observed as a marker in lemongrass oil (0.05%) demonstrating significant inhibitory activity against Staphylococcus aureus.
  2. 02 Identified as a bioactive component in 50% extract formulations providing spatial repellency against Anopheles gambiae.

Transparency

Not commonly dusted
Min. effective
0.05%
Red flag below
0.01%

Because it is an aromatic marker, very low concentrations (under 0.05%) are standard for masking purposes; however, 'angel dusting' is rare as it is a functional fragrance component rather than a primary active claim.


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Exhibits robust chemical stability within typical cosmetic emulsions but requires protection from oxidative stress to maintain its aromatic integrity.

Synergies

  • Essential oils
  • Carrier oils
  • Lemongrass extract

Conflicts

  • Strong oxidizing agents
  • Strong reducing agents
  • Extreme pH levels (<3 or >9)

Safety

CIR Status
Not reviewed
Max tested
2%
Pregnancy
Safe
Sensitization risk Low

Listed in the EU CosIng database (CAS 4884-24-6); usage is typically capped at 2% in fragrance concentrates to ensure skin compatibility.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

A valuable aromatic and masking agent that provides an elegant sensory experience with modest antimicrobial benefits.


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References