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BENZYLCARBAMATO CINNAMIDOISOPENTYL DIPEPTIDE-38 AMIDE.

Valuable / ANTI-SEBUM, FILM FORMING

A sophisticated synthetic peptide engineered to act as a dual-action urban defender for the skin. It creates an invisible, breathable matrix that physically blocks particulate matter while simultaneously recalibrating oil production at the cellular level.

anti-sebum anti-pollution film forming skin conditioning

Science

This peptide employs a biomimetic approach to skin protection: the isopentyl dipeptide-38 amide core modulates sebocyte activity to curb excess lipid synthesis, while the benzylcarbamato and cinnamic acid moieties form a structured film. This film acts as a repulsive shield against PM2.5 (urban dust), preventing pollutant adhesion and the subsequent oxidative carbonylation of skin proteins.


Research

High confidence
Effective range 1–3%
Optimal

2%

Key findings

  1. 01 Clinical trials utilizing a 2% concentration confirmed a significant decrease in surface sebum levels and a quantifiable reduction in the accumulation of urban pollutants.
  2. 02 In-vitro analysis on sebocyte cultures validated a reduction in lipid droplet accumulation, while ex-vivo testing demonstrated protection against protein oxidation and carbonylation.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.5%

As a specialized and high-cost synthetic peptide, it is frequently included at 'label claim' levels (below 0.5%) in mass-market products. To achieve the documented anti-pollution and sebum-regulating benefits, a concentration of at least 1-2% is required.


The Formula

Solubility
Water
Optimal pH 3 – 7.5
0 7 14

Stability

Highly temperature-sensitive; must be incorporated during the cool-down phase at temperatures below 40°C to maintain peptide integrity.

Synergies

  • Antioxidants
  • Chelating agents
  • Hyaluronic acid

Conflicts

  • Strong oxidizing agents
  • Proteolytic enzymes
  • Heat processing above 50°C

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Listed in the EU CosIng database; though not yet formally reviewed by the CIR, current safety data for topical cosmetic application is favorable.


Your Skin

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An essential precision ingredient for urban-dwelling skin types prone to congestion and environmental oxidative stress.


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