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BENZYL ISOAMYL ETHER.

Optional CAS 122-73-6 / PERFUMING

A stable synthetic aromatic ether primarily utilized for its distinct gardenia-like scent profile. Beyond its sensory attributes, it functions as a specialized aromatic solvent that enhances the penetration of specific active compounds.

Perfuming Aromatic Solvent Antimicrobial Potentiator

Science

It acts as a fragrant volatile compound providing green and floral olfactory notes. In functional applications, it serves as a lipophilic solvent and antimicrobial potentiator, aiding the solubility of actives and potentially improving their ability to bypass biological barriers.


Research

Medium confidence
Effective range 0.1–1%
Optimal

1%

Key findings

  1. 01 Human experience testing at 12% concentration demonstrated no significant irritation or sensitization across test subjects.
  2. 02 A 2018 RIFM safety assessment (Belsito et al.) confirmed that dermal exposure at 900 μg/cm² remains below the threshold of toxicological concern (TTC).

Transparency

Not commonly dusted
Min. effective
0.05%
Red flag below
1.5%

As a fragrance and solvent component, it is naturally used at low levels. Concentrations exceeding 1% in facial leave-on products are rare and typically unnecessary for its intended aromatic function.


The Formula

Solubility
Oil
Optimal pH 4 – 12
0 7 14

Stability

Exhibits exceptional stability in high-pH environments, including alkaline cleaning agents. As a Class D peroxide-former, it requires airtight, UV-protected storage to prevent oxidative degradation.

Synergies

  • Antimicrobial agents
  • Lipid-based delivery systems

Conflicts

  • Strong oxidizing agents

Safety

CIR Status
Not reviewed by CIR; safety managed by RIFM/IFRA
Max tested
1%
Pregnancy
Safe
Sensitization risk Low

IFRA standards limit usage to 1% in facial moisturizers. While generally non-irritating at 12%, concentration is strictly controlled in skincare to minimize potential for fragrance-related reactions.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

A highly stable aromatic solvent and fragrance component that provides sensory value and slight penetration enhancement without significant irritation risk.


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