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BENZYL BENZOATE.

Valuable CAS 120-51-4 / ANTIMICROBIAL, PERFUMING, SOLVENT

A multifunctional organic ester derived from the condensation of benzyl alcohol and benzoic acid, primarily utilized as a high-performance solvent and fragrance fixative. While it serves a critical functional role in stabilizing aromatic compounds, it is also a clinically recognized acaricide used to eliminate skin parasites.

solvent perfuming antimicrobial acaricide fixative

Science

In cosmetic applications, it acts as a lipophilic solvent that dissolves poorly soluble materials like synthetic musks and slows the evaporation of volatile fragrance components to extend scent longevity. Therapeutically, it functions as a neurotoxin to mites and lice by penetrating their chitinous exoskeletons and disrupting their nervous system, resulting in paralysis and death.


Research

High confidence
Effective range 2–25%
Optimal

5%

Key findings

  1. 01 A 25% concentration is the clinical standard for treating Sarcoptes scabiei, achieving mite lethality within 5 minutes in vitro.
  2. 02 Formulations at 2% concentration demonstrate 100% mortality rates for house dust mites within a 24-hour period.
  3. 03 Local Lymph Node Assays (LLNA) confirm the ingredient is non-sensitizing at concentrations up to 50%.

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.01%

Benzyl benzoate is rarely used as a 'marketing active' for general skincare; it is typically a functional solvent or a naturally occurring component of essential oils. If a product claims anti-parasitic benefits but contains less than 2%, it is likely under-dosed for that specific therapeutic outcome.


The Formula

Solubility
Oil
Optimal pH 5 – 7
0 7 14

Stability

Highly stable under standard conditions but sensitive to hydrolysis in environments with extreme acidity or alkalinity. It is susceptible to photo-oxidation and air exposure, requiring opaque, airtight packaging.

Synergies

  • Synthetic musks
  • Essential oils
  • Preservative systems

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Alkalis

Safety

CIR Status
Safe as used
Max tested
5%
Sensitization risk Moderate

Classified as one of the 26 regulated fragrance allergens by the EU SCCS. Mandatory labeling is required if the concentration exceeds 0.001% in leave-on products or 0.01% in rinse-off products.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An essential functional component for fragrance stability and ingredient solubility, though its status as a regulated allergen necessitates caution for sensitive skin profiles.


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