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Moumoujus

BENZOYL CHLORIDE.

Avoid CAS 98-88-4 / SKIN CONDITIONING

Benzoyl chloride is a highly volatile chemical intermediate primarily used in the industrial synthesis of cosmetic actives like benzoyl peroxide. Due to its extreme reactivity and corrosive nature, it is strictly an industrial precursor and is never intentionally included in finished skincare formulations.

Summary

chemical intermediate manufacturing precursor

Science

Mechanism of Action

Upon topical contact, this acyl halide reacts violently with moisture in the stratum corneum. This hydrolysis process generates hydrochloric acid and benzoic acid directly on the skin surface, causing rapid protein denaturation and significant tissue destruction.

Research

Clinical Evidence

High confidence
Effective range 0–0%
Optimal

0%

Key findings

  1. 01 Animal sensitization tests at 2-5% concentrations demonstrated a 90% sensitization rate characterized by severe erythema and persistent irritation.
  2. 02 High-concentration dermal exposure in mice models resulted in epidermal necrosis, ulceration, and alopecia.

Transparency

Dusting Analysis

Not commonly dusted
Red flag below
0.0001%

This is a hazardous industrial reagent, not a cosmetic ingredient; any presence in a formula would indicate a dangerous manufacturing failure or contamination.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Extremely unstable; reacts exothermically with water to produce toxic hydrogen chloride gas and benzoic acid.

Conflicts

  • water
  • alcohols
  • amines
  • strong bases
  • oxidizing agents
  • dimethyl sulfoxide (DMSO)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0%
Pregnancy
Caution
Sensitization risk High

Classified as a GHS Category 1B corrosive and a lachrymator. It is prohibited for use in topical applications.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

A hazardous corrosive agent that serves as a manufacturing intermediate and has no place in safe, precision skincare.

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