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Ingredient directory

Benzalkonium Cetyl Phosphate

An advanced, organophilic quaternary ammonium salt that serves as a highly efficient antimicrobial and stabilizing agent. It offers a sophisticated alternative to traditional benzalkonium salts by providing potent antibacterial action with a significantly improved skin-safety profile.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Antimicrobial Antibacterial Deodorant Surfactant pH Stabilizer

Science

As a cationic surfactant, it targets the negatively charged membranes of harmful bacteria and fungi. By adsorbing onto these microbial surfaces, it compromises the lipid bilayer integrity, leading to membrane leakage and the rapid neutralisation of the microorganism.


Research

High confidence
Effective range 0.1–5%
Optimal

2%

Key findings

  1. 01 Demonstrated superior efficacy against Propionibacterium acnes and S. hominis (odor-causing bacteria) while maintaining lower irritation levels compared to standard benzalkonium chloride.

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Because it is effective at concentrations as low as 0.1%, it is rarely 'dusted'; however, for active acne or deodorant claims, levels below 0.1% may not provide the intended clinical antimicrobial benefit.


The Formula

Solubility
Both
Optimal pH 4 – 7
0 7 14

Stability

A complex salt that enhances organophilic compatibility and helps stabilize the final pH of cosmetic emulsions.

Synergies

  • Lipid-based delivery systems
  • Non-ionic surfactants

Conflicts

  • High concentrations of anionic surfactants
  • Strong oxidizing agents
  • Environments with pH below 3.5

Safety

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

Classified as Category III by the FDA for antiseptic washes due to the need for more long-term data, though it is fully permitted for use in the EU CosIng database.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance antimicrobial that bridges the gap between clinical potency and skin comfort, making it ideal for targeted acne and hygiene formulations.


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