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BASIC VIOLET 16.

Questionable CAS 6359-45-1 / HAIR DYEING

Basic Violet 16 is a synthetic cationic methine dye utilized for temporary and semi-permanent hair coloration. It provides high-intensity pigment deposition through surface-level protein binding without requiring chemical developers or deep penetration.

hair dyeing color depositing

Science

This ingredient functions via electrostatic attraction; as a positively charged (cationic) molecule, it binds to the negatively charged surface of keratin found in the hair and the skin's stratum corneum. Due to its significant molecular size and charge, it remains on the surface rather than penetrating the hair shaft or dermal layers.


Research

Medium confidence
Effective range 0.1–1%
Optimal

1%

Key findings

  1. 01 Demonstrated low dermal penetration due to molecular characteristics, though repeated exposure presents a specific risk for skin sensitization.

Transparency

Not commonly dusted
Min. effective
0.05%
Red flag below
0.01%

As a concentrated colorant, it is typically used at functional levels to achieve visible results; however, it has no therapeutic skincare value and is solely a pigment.


The Formula

Solubility
Water
Optimal pH 3 – 5
0 7 14

Stability

The dye is most stable in acidic environments; exposure to alkaline conditions or temperatures exceeding 120°C may cause the hue to shift toward yellow.

Synergies

  • Cationic surfactants
  • Acidic conditioners

Conflicts

  • Oxidizing agents
  • Strong alkalis
  • Nitrosating agents
  • Reducing agents

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Moderate

In the United States, it is restricted exclusively to hair dye products and is not an FDA-certified color additive for general cosmetics. EU regulations limit nitrosamine content to 50 µg/kg.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

While effective for temporary hair toning, Basic Violet 16 is unsuitable for leave-on skincare due to its potential for irritation and lack of biological benefit to the skin.


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