Science
Mechanism of Action
Functions through electrostatic attraction where the positively charged dye molecules bind to negatively charged carboxylate groups found in keratin structures. This allows for surface-level color deposition without the need for chemical oxidation.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 A 2001 case study confirmed that a 1.0% concentration in hair mousse triggered severe allergic contact dermatitis, validated by patch testing.
- 02 QSAR modeling and cluster analysis identified the molecule as a moderate to strong sensitizer among common hair dye substances.
Transparency
Dusting Analysis
As a prohibited substance in many jurisdictions, this ingredient is not typically found in skincare; any inclusion in topical products would represent a significant safety violation rather than marketing 'dusting'.
The Formula
Formulation
Stability
The molecule maintains hydrolytic stability in acidic environments but degrades as the pH approaches neutral or alkaline levels; it is also highly sensitive to chlorine residues in water.
Conflicts
- Anionic surfactants
- Anionic polymers
- Strong oxidizing agents
Safety
Safety Profile
Explicitly prohibited for use in cosmetic products in the European Union (Annex II, entry 1292) and lacks US FDA approval for general cosmetic applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Prohibited in the EU and identified as a potent sensitizer, this ingredient has no place in a precision skincare regimen.
Related
Similar Ingredients
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References
Sources