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BASIC ORANGE 2.

Avoid CAS 532-82-1 / HAIR DYEING

A synthetic cationic azo dye primarily utilized for its ability to deposit color onto keratinous surfaces like hair through physical adsorption. While historically used in coloring preparations, it is currently subject to strict regulatory prohibitions due to significant safety concerns regarding its systemic toxicity.

hair dyeing industrial coloring

Science

As a cationic direct dye, Basic Orange 2 functions through ionic attraction and van der Waals forces. In aqueous solutions, it generates positively charged ions (cations) that are drawn to the negatively charged surface of hair fibers and other substrates, adhering mechanically without requiring a chemical reaction with the surface.


Research

High confidence
Effective range 0.01–2%
Optimal

N/A

Key findings

  1. 01 Clinical patch tests demonstrated that concentrations as low as 0.01% are capable of inducing positive sensitization reactions in human subjects.
  2. 02 Historically used at 2% in hair dyes, but the SCCNFP determined it unsafe for use due to insufficient data regarding its genotoxic and carcinogenic potential.

Transparency

Not commonly dusted
Min. effective
0.01%
Red flag below
0.001%

Because Basic Orange 2 is prohibited in major global markets (EU Annex II) and acts as a potent sensitizer at 0.01%, its presence at any detectable level in a skincare formulation is considered a critical safety violation.


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

The dye is highly sensitive to pH, transitioning from an orange hue at pH 4.0 to a yellow appearance at pH 7.0. It is thermolabile and should not be exposed to excessive heat during processing.

Conflicts

  • Strong oxidizing agents
  • Peroxides
  • Metal salts
  • Sulfides
  • Strong reducing agents
  • Aldehydes

Safety

CIR Status
Not reviewed
Max tested
0%
Pregnancy
Caution
Sensitization risk High

Classified as a 'Danger' substance under GHS; it is suspected of causing genetic defects (H341) and serious eye damage (H318). It is banned for cosmetic use in the European Union, ASEAN, and New Zealand.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Basic Orange 2 is a hazardous hair dye component prohibited in most regions due to genotoxicity risks and a high potential for skin sensitization.


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