Science
Mechanism of Action
The Bacillus fermentation process enzymatically cleaves large marine proteins and polysaccharides into smaller, low-molecular-weight peptides and amino acids. These act as Natural Moisturizing Factors (NMFs) to reduce trans-epidermal water loss while simultaneously scavenging reactive oxygen species (ROS) and providing antimicrobial support to maintain a healthy skin microbiome.
Research
Clinical Evidence
Medium confidence2%
Key findings
- 01 In vivo and in vitro patent studies (KR2012169818A3) confirm significant anti-wrinkle effects and oxidative stress protection via ROS inhibition.
- 02 Bioactive lectins isolated from the extract exhibit potent antimicrobial activity at concentrations as low as 400 µg/mL.
Transparency
Dusting Analysis
Because efficacy begins at very low thresholds (0.01%), many formulations include it at 'label-only' concentrations below 0.005% to claim marine benefits without providing functional antioxidant or moisturizing value.
The Formula
Formulation
Stability
Optimal bioactivity of enzymes like cellulases is maintained between pH 4.5–5.5. Formulators must avoid heating the phase above 50°C to prevent the denaturation of bioactive marine proteins.
Synergies
- Hyaluronic Acid
- Galactomyces Ferment Filtrate
- Niacinamide
Conflicts
- Strong oxidizing agents
- Extremely acidic (pH <3.0) or alkaline (pH >8.0) environments
Safety
Safety Profile
While the CIR is currently collecting data for a full safety assessment (as of 2025), it remains approved for use in the EU and US cosmetic markets with no specific concentration limits.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance marine biotech ingredient that offers multi-target benefits for barrier repair and oxidative protection, though consumers should look for transparent concentration levels.
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