Science
Mechanism of Action
The fermentation process utilizes Bacillus bacteria to enzymatically break down complex Heartleaf polyphenols, such as quercitrin, into smaller molecular weights for superior skin penetration. During this process, Jeju volcanic ash (scoria) releases essential minerals like silica, calcium, and magnesium, which act as catalysts for cellular repair. The resulting filtrate inhibits melanogenesis by downregulating the Microphthalmia-associated transcription factor (MITF) and provides potent anti-inflammatory effects by suppressing nitric oxide production.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 In vitro testing confirmed a 62.19% suppression of MITF, effectively blocking the pathway for melanin production.
- 02 Demonstrated significant reduction in Nitric Oxide (NO) levels in BV-2 cells, indicating powerful anti-inflammatory properties.
- 03 Validated antioxidant activity through comprehensive DPPH and ABTS radical scavenging assays.
Transparency
Dusting Analysis
Due to its sophisticated manufacturing process and dual-action (brightening and soothing) benefits, this ingredient is frequently included in 'marketing doses' below 1%. For measurable suppression of melanogenesis, a minimum concentration of 3% is required.
The Formula
Formulation
Stability
The ingredient is stable in aqueous systems but highly thermosensitive; it must be incorporated during the cooling phase below 40°C to prevent the degradation of bioactive ferment metabolites.
Synergies
- Niacinamide (complementary brightening)
- Hyaluronic acid (hydration delivery)
- Ceramides (barrier repair)
Conflicts
- High manufacturing temperatures (>40°C)
- Strong oxidizing agents
Safety
Safety Profile
Classified as non-toxic and a low-irritant. Its unique volcanic ash processing removes the characteristic pungent odor of Houttuynia, making it suitable for fragrance-free sensitive skin formulations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A multi-functional bio-active that provides a scientifically-backed 62% reduction in pigment-stimulating factors while simultaneously calming inflammatory pathways.
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References
Sources