Science
Mechanism of Action
This microalgal lipid acts as a biological trigger for skin densification. It upregulates the expression of key barrier proteins—specifically Filaggrin, Claudin-1, and Involucrin—to seal the stratum corneum. Furthermore, it penetrates to the dermal layer where it stimulates fibroblasts to increase Type I collagen production, effectively reducing trans-epidermal water loss (TEWL) and improving cutaneous elasticity.
Research
Clinical Evidence
High confidence0.0001%
Key findings
- 01 Clinical testing at a concentration of 1 ppm (0.0001%) demonstrated a significant reduction in periorbital fine lines compared to placebo, alongside measurable increases in Filaggrin expression for barrier repair.
Transparency
Dusting Analysis
Because this ingredient is clinically active at an exceptionally low threshold (1 ppm), it is frequently used in 'marketing doses' that fall below the level required to trigger collagen synthesis or barrier protein upregulation.
The Formula
Formulation
Stability
Contains polyunsaturated fatty acids (DHA/EPA) susceptible to oxidation; must be stabilized with antioxidants like Tocopherol. Pentadecyl® variants utilize specific saturated chains for enhanced shelf-stability.
Synergies
- Tocopherol
- Ceramides
- Peptides
Conflicts
- Strong oxidizing agents
Safety
Safety Profile
Recognized by the FDA as GRAS (Generally Recognized As Safe). Clinical irritation tests show no adverse reactions at therapeutic levels.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An ultra-potent marine bioactive that provides scientifically validated anti-aging and barrier-strengthening benefits even at microscopic concentrations.
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References
Sources