Science
Mechanism of Action
This filtrate functions by inhibiting tyrosinase and down-regulating the MITF pathway to suppress melanin production. Simultaneously, the fermentation-enriched flavonoids like liquiritigenin provide antioxidant protection and inhibit MMP-1 enzymes to prevent collagen degradation.
Research
Clinical Evidence
High confidence10%
Key findings
- 01 In vivo testing demonstrated a dose-dependent increase in skin luminosity and hydration, with a 10% concentration achieving a 29.97% improvement in whitening parameters over 28 days.
- 02 Comparative in vitro analysis confirms that the fermented filtrate exhibits significantly higher tyrosinase and MMP-1 inhibition than non-fermented licorice extract due to elevated flavonoid concentrations.
Transparency
Dusting Analysis
Because fermented extracts are premium ingredients, they are often included at token amounts (<0.1%) for marketing claims. Efficacy for significant brightening typically requires a minimum of 1.0%.
The Formula
Formulation
Stability
The fermentation process inherently stabilizes the botanical actives against oxidation; however, the filtrate should not be exposed to extreme acidity to prevent protein precipitation.
Synergies
- Niacinamide
- Vitamin C
- Hyaluronic Acid
Conflicts
- Strong oxidizing agents
- pH levels below 3.0
Safety
Safety Profile
While the specific filtrate is emerging, its constituent parts (Licorice and common ferments) have a long-standing history of safety in cosmetic applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance brightening agent that offers superior absorption and multi-pathway efficacy compared to traditional licorice extracts.
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References
Sources