ASPERGILLUS/(OLIVE FRUIT/LEAF/SEED)/RICE FERMENT FILTRATE.

This ingredient harnesses the synergistic benefits of fermented rice and olive, enhanced by Aspergillus. The fermentation process amplifies the bioavailability of beneficial compounds, including amino acids, vitamins, natural peptides, enzymes, and Natural Moisturizing Factors (NMFs). The rice component actively boosts hydration by upregulating Aquaporin 3 (AQP3) and Hyaluronan Synthase 1 (HAS1) mRNA expression, while strengthening the skin barrier through increased Claudin 1 (CLDN1), Involucrin (IVL), and Zonula Occludens-1 (ZO-1) mRNA expression in keratinocytes, complemented by naturally occurring ceramides and Filaggrin (FLG). It stimulates fibroblast proliferation and enhances mRNA expression of ECM-related anti-aging genes, promoting collagen synthesis and improving skin texture. Additionally, it exhibits potent antioxidant activity by reducing reactive oxygen species, provides anti-inflammatory benefits, and contributes to skin brightening by inhibiting melanin synthesis and tyrosinase activity. The olive component, post-fermentation, demonstrates increased levels of phenolic compounds such as hydroxytyrosol and elenolic acid derivatives, further augmenting its robust antioxidant and protective capabilities.