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Moumoujus

ARALIA NUDICAULIS ROOT EXTRACT.

Valuable CAS 223749-20-0 / SKIN CONDITIONING

Aralia Nudicaulis Root Extract, derived from the wild sarsaparilla plant, is a botanical ingredient recognized for its potent antioxidant and anti-inflammatory properties. It provides cellular protection against environmental aggressors and supports overall skin vitality.

Summary

Antioxidant Anti-inflammatory Skin conditioning Photoprotective Soothing Acne management (traditional basis)

Science

Mechanism of Action

This extract operates primarily through its rich content of phenolic compounds, including chlorogenic, caffeic, and protocatechuic acids. These active components effectively inhibit the generation of reactive oxygen species (ROS) induced by UV-B and IR-A radiation, thereby shielding dermal cells from oxidative stress. Saponins further contribute to its anti-inflammatory effects, while traditional uses suggest potential benefits for acne due to its ability to modulate excess androgen levels.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An enriched fraction of phenolic compounds, containing 15.6% chlorogenic acid, 15.3% caffeic acid, and 4.8% protocatechuic acid (of total FEPC composition), demonstrated significant antioxidant and anti-inflammatory activities. This fraction strongly inhibited reactive oxygen species (ROS) generation induced by IR-A and UV-B in human skin fibroblasts, indicating protection against oxidative stress.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

While antioxidant activity was observed in experimental conditions at pH 7.4, the specific optimal pH range for the extract's stability in a final formulation is not provided. As with many plant extracts rich in phenolic compounds, it may exhibit sensitivity to pH fluctuations, light, and oxidation.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Aralia Nudicaulis root is listed in the FDA Global Substance Registration System (GSRS) with a recognized UNII (JBC3E2Y883). However, a comprehensive safety assessment by the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS) is currently unavailable.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Aralia Nudicaulis Root Extract is a valuable botanical offering significant antioxidant and anti-inflammatory benefits for skin protection and soothing, though more comprehensive safety data and specific efficacy concentrations for cosmetic use would enhance its profile.

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