Science
Mechanism of Action
This extract operates as a multi-target agent; it utilizes mangiferin and iriflophenone glycosides to neutralize free radicals and inhibit glycation. It demonstrates specific antimicrobial activity by disrupting the cell walls of Staphylococcus epidermidis and assists in cellular recovery by accelerating the clearance of UV-induced DNA damage (cyclobutane pyrimidine dimers).
Research
Clinical Evidence
High confidence0.2%
Key findings
- 01 A 2024 double-blind trial confirmed that 0.2% concentration in a facial mask increased skin hydration from 30.9 to 45.9 units over 8 weeks.
- 02 In vitro analysis established a Minimum Inhibitory Concentration (MIC) of 6 mg/ml against S. epidermidis, preventing biofilm formation through bacterial wall rupture.
Transparency
Dusting Analysis
Because of its high efficacy at very low concentrations (0.1%-0.2%), many formulations include it at 'label-only' levels below 0.05% where clinical hydration benefits may not be fully realized.
The Formula
Formulation
Stability
Exceptional stability profile; the extract remains chemically resilient across a vast pH spectrum, making it a pH-independent active suitable for diverse product formats.
Synergies
- Hyaluronic acid
- Niacinamide
- UV filters
Safety
Safety Profile
Clinically tested as non-irritating at 0.1% and 0.2%. Higher concentrations (1%+) may lead to mild irritation in reactive skin types.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly stable, precise botanical active that offers significant hydration and microbiome-balancing benefits at remarkably low concentrations.
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