Science
Mechanism of Action
This dipeptide acts as a molecular scavenger for reactive oxygen species (ROS) and hypochlorous acid (HClO), neutralising oxidative stress before it damages the cellular matrix. It prevents the formation of Advanced Glycation End-products (AGEs) by shielding proteins from sugar-induced cross-linking, while simultaneously regulating pigment production by inhibiting tyrosinase via the ERK signaling pathway.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Clinical evaluation of enriched fish extracts demonstrated significant protection against UV-induced photoaging and oxidative damage at concentrations between 1.38% and 10.6%.
- 02 Dose-dependent studies indicate a significant reduction in melanogenesis through targeted tyrosinase inhibition.
Transparency
Dusting Analysis
Due to its higher manufacturing cost and dipeptide nature, anserine is often included at 'label-claim' concentrations below 0.1%. Evidence suggests effective photo-protection and pigment regulation require concentrations starting at approximately 1.38%.
The Formula
Formulation
Stability
Highly stable across physiological pH ranges. Unlike carnosine, its methylated structure grants it resistance to carnosinase enzymes, ensuring longer-lasting activity in the skin. It is hygroscopic and requires protection from light and heat.
Synergies
- Carnosine
- Vitamin C
- Broad-spectrum UV filters
- Hyaluronic Acid
Conflicts
- Strong oxidizing agents
- pH environments below 3.0
- pH environments above 9.0
Safety
Safety Profile
As a naturally occurring dipeptide, it is exceptionally well-tolerated and biologically compatible.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly stable and multi-functional dipeptide essential for precision anti-aging and defense against environmental photo-damage.
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References
Sources