Science
Mechanism of Action
This extract inhibits melanin and tyrosinase activity while modulating macrophage activation to reduce inflammation via the Calcium–STAT3 pathway. It also combats photoaging by increasing procollagen and decreasing MMP-1 and elastase, thus promoting tissue repair.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Journal of Microbiology and Biotechnology (2018), 28(7): 1061–1067
- 02 Journal of Microbiology and Biotechnology (2018), 28(8): 1391–1400
- 03 MDPI Molecules/Antioxidants (2022)
- 04 F1000Research (2021/2022 Review)
Transparency
Dusting Analysis
No specific data suggests this ingredient is commonly dusted in formulations; its efficacy is observed at tested concentrations.
The Formula
Formulation
Stability
The extract's volatile components, like Z-ligustilide, are sensitive to heat and oxidation. Fermentation is often employed to enhance the concentration and stability of active metabolites.
Conflicts
- Strong oxidizing agents
- Extreme pH conditions (may degrade delicate phthalides like ligustilide)
Safety
Safety Profile
While not formally reviewed by the CIR, this extract is widely used in South Korean 'Hanbang' cosmetics. In vitro studies confirm no cytotoxicity up to 1000 μg/mL, suggesting a favorable safety profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Angelica Tenuissima Root Extract is a valuable, multi-beneficial ingredient for skin brightening, anti-aging, soothing, and repair across all skin types.
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References
Sources