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ANGELICA SHIKOKIANA LEAF/ROOT EXTRACT.

Valuable / ANTIOXIDANT

Angelica Shikokiana Leaf/Root Extract, also known as Japanese Mountain Ginseng, is a botanical powerhouse offering significant antioxidant and skin-brightening benefits. It helps to protect the skin from oxidative stress while promoting a more even tone.

antioxidant skin conditioning

Science

This extract inhibits tyrosinase, the enzyme crucial for melanin production, through bioactive coumarins and flavonoids like isopteryxin. It also provides neuroprotective and anti-inflammatory benefits by scavenging reactive oxygen species.


Research

Medium confidence
Effective range 0.1–1%
Optimal

1%

Key findings

  1. 01 In vitro studies showed 0.1% - 1.0% extract inhibited tyrosinase and reduced melanin synthesis.
  2. 02 Extract demonstrated high antioxidant capacity via radical scavenging.
  3. 03 In vivo studies indicated microcirculation benefits, though direct skin-topical human data is limited.

Transparency

Not commonly dusted

No evidence suggests this ingredient is frequently underdosed. Its documented in vitro efficacy supports its use within studied concentrations.


The Formula

Solubility
Both
Optimal pH 5 – 7
0 7 14

Stability

Contains heat-sensitive compounds; supercritical CO2 extraction is preferred. Best stability is in slightly acidic to neutral pH, avoid temperatures above 60°C.

Conflicts

  • Strong oxidizing agents
  • Strongly alkaline environments (may degrade coumarin structures)

Safety

CIR Status
Not reviewed
Sensitization risk Low

Not formally reviewed by CIR, but traditionally used as a dietary supplement. Toxicological studies show no significant cytotoxicity at standard concentrations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A promising antioxidant and brightening extract, effectively inhibiting melanin production and protecting against oxidative stress for a radiant, even complexion.


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References